What are NSAIDs typically used for?

NSAIDs, or nonsteroidal anti-inflammatory drugs, are primarily utilized for their ability to relieve pain, reduce inflammation, and lower fever. This class of medications includes common drugs such as ibuprofen, naproxen, and aspirin. Their mechanism of action involves inhibiting the activity of cyclooxygenase enzymes (COX-1 and COX-2), which play a crucial role in the conversion of arachidonic acid to prostaglandins. Prostaglandins are chemicals in the body that promote inflammation, pain, and fever, hence by reducing these mediators, NSAIDs effectively alleviate discomfort associated with various conditions.

These medications are commonly prescribed for conditions like arthritis, muscle pain, menstrual cramps, and headaches. Additionally, their antipyretic properties make them useful in managing fever during illnesses. While NSAIDs are widely used in many clinical situations due to their effectiveness, they do not serve the roles associated with blood pressure management, depression treatment, or diabetes management, which are addressed by different classes of medications.