What is a common side effect of statins?

Muscle pain is a well-documented side effect associated with statin medications, which are commonly prescribed to help manage cholesterol levels and reduce the risk of cardiovascular disease. Statins work by inhibiting an enzyme involved in the production of cholesterol in the liver. One of the ways in which they may lead to muscle pain is through a mechanism involving muscle cell metabolism and inflammation, possibly disrupting the integrity of muscle fibers. This condition, known as statin-related myopathy, can range from mild discomfort to severe muscle injury.

While other potential side effects of statins exist, they are less commonly reported compared to muscle-related symptoms, which is why muscle pain is considered a hallmark side effect. This side effect can significantly impact the quality of life and adherence to medication regimens. It is important for patients to communicate with healthcare providers about any muscle discomfort when taking statins, as dose adjustments or alternative medications may be necessary.