What is a common side effect associated with gentamycin?

Prepare for the Houston Methodist Pharmacology Exam. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready to ace your test!

Gentamicin is an aminoglycoside antibiotic commonly used to treat serious infections caused by gram-negative bacteria. One significant and well-documented side effect associated with gentamicin is ototoxicity. This condition involves damage to the auditory system and can lead to hearing loss or balance issues, which is especially concerning in patients receiving prolonged treatment or high doses of the drug.

Ototoxicity occurs because gentamicin interacts with the inner ear structures, specifically affecting the hair cells in the cochlea and vestibular apparatus. This side effect can be particularly problematic, as it may be irreversible in some cases, making monitoring patients' hearing and balance during therapy crucial.

While gentamicin can also have nephrotoxic effects—another serious side effect that involves damage to the kidneys—the primary association and risk that often comes to mind with gentamicin is its potential to cause ototoxicity. Careful dose management and monitoring of renal function can help mitigate this risk.

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