What is a common use for SSRIs?

Selective Serotonin Reuptake Inhibitors (SSRIs) are commonly prescribed for major depressive disorder (MDD) due to their effectiveness in increasing serotonin levels in the brain, which can help alleviate symptoms of depression. MDD is characterized by persistent feelings of sadness, loss of interest, and a range of emotional and physical problems that affect a person’s ability to function in daily life. SSRIs work by blocking the reabsorption (reuptake) of serotonin in the brain, making more serotonin available to improve neurotransmission.

While SSRIs are also utilized for various other conditions, such as anxiety disorders (which may encompass social anxiety disorder) and sometimes for insomnia, their primary indication and the condition for which they are most commonly prescribed remain major depressive disorder. This use is supported by a substantial body of clinical research, demonstrating their efficacy and safety in treating depression compared to other pharmacological treatments.