What is a common use for the medication sildenafil?

Prepare for the Houston Methodist Pharmacology Exam. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready to ace your test!

Sildenafil is commonly known for its use in the treatment of erectile dysfunction. It works by inhibiting phosphodiesterase type 5 (PDE5), which results in increased blood flow to the penis during sexual stimulation. This enhanced blood flow facilitates the achievement and maintenance of an erection. The effectiveness of sildenafil in this context has made it one of the most well-known treatments for erectile dysfunction, widely prescribed and recognized for its action in supporting sexual health.

In addition to treating erectile dysfunction, sildenafil is also utilized in specific cases of pulmonary hypertension, where it helps relax blood vessels in the lungs to improve exercise capacity and reduce symptoms. However, its primary and most recognized indication remains the management of erectile dysfunction in men. Other options, such as anxiety disorders or asthma, do not align with the pharmacological action or therapeutic targets of sildenafil.

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