What is a potential outcome of administering SNRIs in terms of risks?

Prepare for the Houston Methodist Pharmacology Exam. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready to ace your test!

Administering serotonin-norepinephrine reuptake inhibitors (SNRIs) can indeed carry an increased risk of bleeding. This effect is attributed to the way SNRIs can impact platelet function. Specifically, they may reduce serotonin uptake by platelets, which is crucial for proper platelet aggregation and function. A decrease in serotonin levels in platelets can lead to an impairment in the ability of the platelets to clump together effectively, thereby increasing the risk of bleeding in patients who are on SNRIs, especially in those who may be taking additional medications that also have anticoagulant effects or have existing bleeding disorders. This highlights the importance of monitoring patients for signs of bleeding if they are prescribed SNRIs.

The other potential outcomes listed do not have a strong direct correlation with the mechanism of action or the known side effects of SNRIs. While psychosis is generally more associated with other class medications (like high-dose steroids or certain stimulants), hypoglycemia is primarily a concern with antidiabetic medications rather than with SNRIs. Decreased renal function can occur with various drugs, but it's not a prominent risk associated specifically with SNRIs. Thus, increased risk of bleeding stands out as the most relevant outcome linked to S

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