What is monitored when a patient is on Coumadin?

When a patient is on Coumadin (warfarin), it is essential to monitor the International Normalized Ratio (INR) to ensure the medication is maintaining its therapeutic effect without increasing the risk of bleeding. The INR is a standardized measure used to evaluate the coagulation status of patients on anticoagulant therapy. A specific target INR range is determined based on the patient's condition, such as atrial fibrillation or a history of thrombosis, and requires regular monitoring to adjust the dose of Coumadin accordingly.

Vitamin K levels, while not routinely monitored as closely as INR, are relevant because they are involved in the synthesis of clotting factors that Coumadin inhibits. A high intake of vitamin K can counteract the effects of warfarin, making it necessary to maintain a consistent dietary intake of vitamin K during treatment.

Other monitoring parameters may be useful in clinical management, but they do not play as direct a role in warfarin therapy management as INR. For instance, blood glucose levels pertain to diabetes management, and liver enzymes are relevant for assessing liver function, which can affect warfarin metabolism. Platelet counts can help evaluate thrombocytopenia but are not a primary focus in monitoring warfarin therapy. The main