What should be closely monitored in patients taking SSRIs?

In patients taking selective serotonin reuptake inhibitors (SSRIs), it is crucial to closely monitor for suicidal tendencies due to the risk of increased suicidal ideation, particularly in certain populations, such as adolescents and young adults. SSRIs can cause a paradoxical increase in anxiety or agitation, which may contribute to these thoughts. The monitoring should encompass routine assessments of mood, behavior changes, and any expressions of self-harm. Awareness of these risks is essential for ensuring patient safety, especially during the initial treatment period when the medication may be starting to take effect or when doses are changed.

The other options, while relevant in different contexts, do not carry the same level of immediate concern specifically associated with SSRIs as monitoring for suicidal tendencies. Blood pressure and heart rate changes can occur with various medications, but they are not typically a primary focus with SSRIs. Liver enzymes might be monitored if there is a known risk of liver dysfunction, but this is generally less of a concern with SSRIs compared to their association with mood changes. Electrolyte levels are important to consider, particularly in patients who might be dehydrated or at risk for electrolyte imbalances due to other factors, but again, this is not as directly related to SSRIs as the need to