What type of insulin does typically NOT have a peak action?

Very long-acting insulin, also known as ultra-long-acting insulin, is designed to provide a stable and consistent release of insulin over an extended period, usually lasting up to 24 hours or more. This type of insulin works by maintaining a steady level of insulin in the bloodstream without sharp increases in action, which means it does not have a distinct peak action like other forms of insulin.

This characteristic is especially beneficial for individuals with diabetes as it helps to maintain basal insulin levels, providing a continuous supply that helps to control blood sugar levels throughout the day and night. The absence of a peak allows for greater flexibility in lifestyle and meal timing, reducing the risk of hypoglycemia related to insulin peaks that can occur with other types of insulin.

Short-acting insulin, intermittent insulin, and regular insulin are characterized by specific peak action times that correspond to their pharmacokinetic profiles, which contribute to their effectiveness in controlling postprandial blood glucose spikes.