Which of the following is classified as an SSRI?

Sertraline is classified as a selective serotonin reuptake inhibitor (SSRI). SSRIs work by increasing the level of serotonin in the brain by inhibiting its reuptake into the presynaptic cell, which enhances mood and alleviates symptoms of depression and anxiety. Sertraline is commonly prescribed for various conditions, including major depressive disorder, anxiety disorders, and obsessive-compulsive disorder.

The other options listed have different classifications and mechanisms of action. Venlafaxine, for example, is an antidepressant that primarily acts as a serotonin-norepinephrine reuptake inhibitor (SNRI). Duloxetine is also an SNRI, used for treating depression and anxiety as well as chronic pain conditions. Mirtazapine belongs to a different class known as noradrenergic and specific serotonergic antidepressants (NaSSAs), which work through a distinct mechanism that involves both blocking certain serotonin receptors and enhancing norepinephrine release.

Understanding these classifications helps clinicians select the appropriate medication based on specific patient needs and the pharmacological profiles of each drug.