Which of the following side effects is NOT typically associated with the use of MAOIs?

Monoamine oxidase inhibitors (MAOIs) are a class of antidepressants known for their unique mechanism of action, which involves inhibiting the enzyme monoamine oxidase, responsible for breaking down neurotransmitters such as serotonin, norepinephrine, and dopamine. This inhibition can lead to increased levels of these neurotransmitters in the synaptic cleft and is therapeutically beneficial for treating certain types of depression.

Among the typical side effects associated with MAOIs, insomnia, weight gain, and postural hypotension are commonly reported. Insomnia may arise from increased norepinephrine levels, which can interfere with sleep patterns. Weight gain can also be a side effect, potentially linked to changes in appetite and metabolism. Postural hypotension, which is a drop in blood pressure upon standing, is another well-known side effect related to the blocking of norepinephrine breakdown, impacting blood vessel constriction.

Ototoxicity, on the other hand, refers to damage to the auditory system or vestibular system due to exposure to certain medications or chemicals. It is not classically associated with MAOIs. There is no strong evidence or significant clinical reports linking the use of MAOIs with ototoxic effects, making this the correct choice in identifying